http://www.tu-braunschweig.de http://sfb578.tu-braunschweig.de
Management
Members
Aims
Project Areas
Publications
Press
Prizes
Dates
Contact
Imprint
 

Aims

The Collaborative Research Center SFB 578 "Development of Biotechnological Processes by Integrating Genetic and Engineering Methods – From Gene to Product –", aims at combining and integrating methods available both from the basic sciences and the fundamental engineering sciences, notably genetics and biochemical engineering, to obtain high value-added products. The work primarily concerns processes for the microbial production of new heterologous proteins by recombinant production strains. The bacteria Escherichia coli (gram-negative) and Bacillus megaterium (gram-positive) as well as the mycelium-forming fungus Aspergillus niger are used as host organisms. The products under study are either pharmaceutically active (antibodies, bone morphogenetic proteins) or serve as biocatalysts to synthesize new oligosaccharides.