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D2 Mikrochips für die Proteinanalytik und -diagnostik

(Büttgenbach/Dübel)

(ab 2. Förderphase)

Publikationen/ Publications

2011

A. Balck, M. Michalzik, L. Al-Halabi, S. Dübel, S. Büttgenbach. (2011). Design and Fabrication of a Lab-on-a-chip for Point-of-care Diagnostics. Sensors & Transducers Journal, Vol. 127, Issue 4, S.102-111

2009

Büttgenbach, S., Balck, A., Demming, S., Lesche, C., Michalzik, M., Al-Halhouli A.T. (2009). Development of on Chip Devices for Life Science Applications. International Journal of Engineering, Vol. 3 (2009) 148-158

S. Büttgenbach,  A. Balck, S. Demming, N. Lucas, M. Michalzik. (2009). Softlithografie – der schnelle Weg zum Lab on Chip. Mikroproduktion,   Vol. 5,   2009,   S. 16-20

Hust, M., Steinwand, M., Al-Halabi, L., Helmsing, S., Schirrmann, T. and Dübel, S. (2009). Improved microtitre plate production of single chain Fv fragments in Escherichia coli. New Biotechnology 25, 424-428

2008

Schirrmann, T., Al-Halabi, L., Dübel, S. and Hust, M. (2008). Production systems for recombinant antibodies. Frontiers in Bioscience 13, 4576-4594

2007

Michalzik, M., Balck, A., Al-Halabi, L., Hust, M., Dübel, S. and Büttgenbach, S. (2007). Massenfließsystem zur CRP-Diagnostik. Proc. Mikrosystemtechnikkongress 2007

Ayala, V.C., Michalzik, M., Harling, S., Menzel, H., Guarnieri, F.A., Büttgenbach, S. (2007). Design, Construction and Testing of a Monolithic pH-Sensitive Hydrogel-Valve for Biochemical and Medical Application. Journal of Physics: Conference Series 90, 012025

2006

Michalzik, M. (2006). Mikrosensorsystem für die Online-Analytik. Technologie- Informationen nieder-sächsischer Hochschulen, Sensorik, Heft 2-2006, 3

Michalzik, M., Balck, A., Büttgenbach, S., Al-Halabi, L., Hust, M. and Dübel, S. (2006). Microsensor System for Biochemical and Medical Analysis. Proc. XX Eurosensors, 420-421

Büttgenbach, S., Michalzik, M., Wilke, R. (2006). New Approaches to On-line Bio Process Monitoring. Engineering in Life Science 6, 449-454

2005

Llobera, A., Wilke, R., Johnson, D. W., Büttgenbach, S. (2005). Polymer microlenses with modified micromolding in capillaries technology. Photonics Technology Letters, IEEE, Vol. 17, 12, 2628 - 2630

Michalzik, M., Wilke, R., Büttgenbach, S. (2005). Miniaturized QCM-Based Flow System for Immunosensor Application in Liquid. Sensors and Actuators B 111-112, 410-415

Michalzik, M., Wendler, J., Rabe, J., Büttgenbach, S., Bilitewski, U. (2005). Development and application of a miniaturized quartz crystal microbalance (QCM) as immunosensor for bone morphogenetic protein-2. Sensors and Actuators B 105, 508-515

Llobera, A., Wilke, R., Büttgenbach, S. (2005). Optimization of Poly(dimethylsiloxane) Hollow Prisms for Optical Sensing. Lab on a Chip 5, 506-511

Büttgenbach, S., Michalzik, M., Wilke, R. (2005). Neue Ansätze zur Online-Bioprozessanalytik. Chemie Ingenieur Technik 77, 833-839

Büttgenbach, S., Wilke, R. (2005). A capillary electrophoresis chip with hydrodynamic sample injection for measurements from a continuous sample flow. Analytical and Bioanalytical Chemistry 383, 733-737

2004

Llobera, A., Wilke, R., Büttgenbach, S. (2004). Two-Regime Hollow PDMS Abbe Prism for µ-TAS Applications. Proc. NSTI-Nanotech 1, 390-393

Llobera, A., Wilke, R., Büttgenbach, S. (2004). Poly (dimethylsiloxane) hollow Abbe prism with microlenses for detection based on absorption and refractive index shift. Lab on a Chip 4, 24 – 27

 

Vorträge und Poster/ Conference Presentations

2009

L. Al-Halabi, D. Fröde, A. Balck, M. Michalzik, M. Hust, S. Büttgenbach, S. Dübel: Recombinant Antibodies for Lab-on-Chip, Proc. VAAM-Tagung 2009 (Sonderausgabe der BIOSpektrum), Bochum, 2009, März, S. 217

S. Demming,  A. Balck, R. Emeis, A. T. Al-Halhouli, S. Büttgenbach. PDMS Micro Components for Separation of Biomass in Lab-on-a- Chip Applications. Mikrosystemtechnik Kongress 2009,  Berlin,  2009,  Oktober,   S. 513-516

Balck, A., Michalzik, M., Al-Halabi, L., Dübel, S., Büttgenbach, S. (2009). Surface modification of a quartz crystal microbalance sensor for detection of C-reactive protein. EnFi-2009, Hasselt, Belgien, 55 (2009)

Büttgenbach, S., Balck, A., Demming, S., Lesche, C., Al-Halhouli, A. T. (2009). A Survey of Microfluidic Devices Fabrication Technology at the IMT. ICTEA09, Abu Dhabi

A. Balck, A. T. Al-Halhouli, S. Büttgenbach. Separation of Red Blood Cells in Y-Microchannels. ICTEA09, Abu Dhabi, 2009, Januar

2008

Michalzik, M., Balck, A., Ayala, C., Lucas, N., Demming, S., Phataralaoha, A., Büttgenbach, S. (2008). A Hydrogel-Actuated Microvalve for Medical and Biochemical Sensing. Actuator 08, Bremen, HVG Bremen, ISBN 3-933339-10-3, 803-806

Michalzik, M., Al-Halabi, L., Balck, A., Hust, M., Dübel, S., Büttgenbach S. (2008). A mass sensitive microfluidic immunosensor for CRP-detection using functional monolayers. Biosensors 2008, Shanghai, P1.72

2007

Michalzik, M., Balck, A., Al-Halabi, L., Hust, M., Dübel, S., Büttgenbach, S. (2007). Massenfließsystem zur CRP-Diagnostik. Proc. Mikrosystemtechnikkongress 2007, Berlin, 939-942

Ayala, V.C., Michalzik, M., Harling, S., Menzel, H., Guarnieri, F.A., Büttgenbach, S. (2007). Design, Construction and Testing of a Monolithic pH-Sensitive Hydrogel-Valve for Biochemical and Medical Application. Proc. SABI, XVI Congreso Argentino de Bioingeniera, San Juan, 171-174

2006

Balck, A., Michalzik, M., Demming, S., Büttgenbach, S. (2006). Miniaturisierter Quarzsensor für die Online-Analytik in Flüssigkeiten. Colloquium für Produktionsintegrierte Wasser-/ Abwassertechnik, Bremen

Michalzik, M., Balck, A., Büttgenbach, S., Al-Halabi, L., Hust, M., Dübel, S. (2006). Microsensor System for Biochemical and Medical Analysis. Proc. XX Eurosensors, Göteborg, 420-421

Michalzik, M., Balck, A., Demming, S., Büttgenbach, S. (2006). Miniaturisierter Quarzsensor für die Online Analytik in Flüssigkeit. Jahrestagung Mikrosysteme für die Biotechnologie, Bremen

Al-Halabi, L., Michalzik, M., Balck, A., Hust, M., Büttgenbach, S., Dübel, S. (2006). Microfluidic Antibody Lab-on-chips. Braunschweig Antibody-Workshop 2006

M. Hust, M. Kirsch, A. El-Ghezal, L. Al-Halabi, T. Bruun, T. Rülker, S. Dübel, T. Schirrmann (2006). A cassette vector system for scFv phage display, production in E.coli and production of scFv-Fc fusion proteins in mamalian cells. Antibody Engineering and Immunotherapeutics for the 21st Century, December 10 - 14, 2006, San Diego Convention Center, San Diego, CA

2005

Al-Halabi, L., El-Ghezal, A., Jordan, E., Hust, M., Jostock, T., . Dübel, S. (2005). Recombinat antibodies: targets and tools of system biology. GVC Vortrags- und Diskussionstagung, Systembiotechnologie

 

2004

S. Büttgenbach, M. Michalzik, R. Wilke. Online Bioprozessanalytik mit Mikrosystemen. Proc. 12. Heiligenstädter Kolloquium, Bad Heiligenstadt, 39-46

Wilke, R., Büttgenbach, S. (2004). A Microsystem for On-line Monitoring of Bio Processes. Proc. 8th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences, Vol.1, Malmö, 183-185

Michalzik, M., Wilke, R., Büttgenbach, S. (2004). Miniaturized QCM-Based Flow System for Immunosensor Application in Liquid. Proc. XVIII Eurosensors, Rome, 275-276

Wilke, R., Michalzik, M., Rabe, J., Büttgenbach, S. (2004). Analytik mit Mikrosystemen auf Basis von Quarzmikrowaagen (QCM) und Kapillarelektrophorese (CE). 2.Workshop Chemische und biologische Mikrolabortechnik, Ilmenau

 

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