http://www.tu-braunschweig.de http://sfb578.tu-braunschweig.de
Geschäftsführung
Mitglieder
Ziele
Projektbereiche
Publikationen
Presse
Preise
Termine
Kontakt
Impressum

B11 Dynamik metabolischer Netzwerke zur Produktion rekombinanter Glycosyltransferasen

(Wittmann)

Publikationen/ Publications

2011

Korneli C, Bolten C J, Godard T, Franco-Lara E, Wittmann C (2012) Debottlenecking recombinant protein production in Bacillus megaterium under large scale conditions - targeted precursor feeding designed from metabolomics. Biotechnol. Bioeng. 109:1538-1550.

Melzer G, Driouch H, Wittmann C (2011) Systems-level design of filamentous fungi; integration of in silico flux modes and in vivo pathway fluxes towards desired production properties. The 26th Fungal Genetics Conference, March 15-20, Asilomar, CA, USA

Biedendieck R., Borgmeier C., Bunk B., Stammen S., Scherling C., Meinhardt F., Wittmann C., Jahn D. (2011) Systems biology of recombinant protein production using Bacillus megaterium. Methods in Enzymology. In press.

2010

Driouch. H., Wittmann. C. (2010) Design and Engineering of Cellular Morphology in Aspergillus niger for Superior Enzyme Production. ,,DECHEMA Vortrags- und Diskussionstagung: Bioprozessorientiertes Anlagendesign’’. 10. ‑ 12. Mai 2010, Nürnberg- Germany.

Driouch H., Roth A., Dersch P., Wittmann C. (2010) Filamentous fungi in good shape: Microparticles for tailor-made fungal morphology and enhanced enzyme production. Bioengineered Bugs 2:1-5.

Driouch H., Roth A., Dersch P., Wittmann C. (2010) Optimized bioprocess for production of fructofuranosidase by recombinant Aspergillus niger .Appl. Microbiol. Biotechnol. 87:2011-2024.

Melzer G., Eslahpazir M., Franco-Lara E. and Wittmann C. (2010). Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties. BMC Systems Biology, 3:120.

Driouch H., Sommer B., and Wittmann C. (2010). Morphology engineering of Aspergillus niger for improved enzyme production. Biotechnology Bioengineering, 105:1058 - 1068.

2009

Melzer G, Eslahpazir M, Franco-Lara E, Nörtemann B, Hempel DC, Wittmann C (2009) Elementary mode analysis of Aspergillus niger metabolic network for optimization of recombinant sucrase production. 27th DECHEMA Jahrestagung der Biotechnologen, 08. – 10. September, Mannheim, Deutschland

 

Vorträge und Poster/ Conference Presentations                                                                                                 

2010

Driouch. H., Sommer. B., Roth. A..,Dersch. P., Wittmann. C. (2010) Targeted Morphology Engineering of Aspergillus niger for Improved Enzyme Production. ,,10th European Conference on fungal genetics ECFG’’. 29‑.März 01-.April 2010, Amsterdam, Holland.

Driouch. H., Wittmann. C. (2010) Design and Engineering of Cellular Morphology in Aspergillus niger for Superior Enzyme Production. ,,DECHEMA Vortrags- und Diskussionstagung ‚‚Bioprozessorientiertes Anlagendesign’’. 10. -12. Mai 2010, Nürnberg- Germany

Driouch. H., Melzer, G. Sachs, J. H., Wittmann. C (2010) Dynamik metabolischer Netzwerke zur Produktion rekombinanter Glycosyltransferasen. ’’100 Kolloquium’’ der Sonderforschungsbereich 578, TU Braunschweig, 28. Juni 2010, Braunschweig, Germany

2009

Melzer G, Eslahpazir M, Franco-Lara E, Nörtemann B, Hempel DC, Wittmann C (2009) Advanced in silico analysis of Aspergillus niger metabolic network for optimization of the fructofuranosidase production. 14th European congress on biotechnology, September 13 – 16, Barcelona, Spain     

Driouch. H., Sommer. B., Wittmann. C. (2009) Morphology Engineering of Apsergillus niger for Improved Enzyme Production using Microparticles of Talc. ,,14th European Congress on Biotechnology: SYMBIOSIS-Science, Industry and Society’’. 13.-16. September 2009, Barcelona, Spain.

 


<< zurück zum Überblick / back